| Rank | Title | Weekend | Total |
| 1. | Teenage Mutant Ninja Turtles: Out of the Shadows | $35,250,000 | $35,250,000 |
| 2. | X-Men: Apocalypse | $22,325,000 | $116,498,232 |
| 3. | Me Before You | $18,270,000 | $18,270,000 |
| 4. | Alice Through the Looking Glass | $10,691,000 | $50,772,597 |
| 5. | The Angry Birds Movie | $9,775,000 | $86,677,726 |
| 6. | Captain America: Civil War | $7,591,000 | $388,940,157 |
| 7. | Neighbors 2: Sorority Rising | $4,700,000 | $48,560,225 |
| 8. | Popstar: Never Stop Never Stopping | $4,630,000 | $4,630,000 |
| 9. | The Jungle Book | $4,247,000 | $347,469,661 |
| 10. | The Nice Guys | $3,520,000 | $29,120,850 |
vía BoxOfficeMojo
