| Rank | Title | Weekend | Total |
| 1. | X-Men: Apocalypse | $65,000,000 | $65,000,000 |
| 2. | Alice Through the Looking Glass | $28,112,000 | $28,112,000 |
| 3. | The Angry Birds Movie | $18,700,000 | $66,353,309 |
| 4. | Captain America: Civil War | $15,125,000 | $372,610,948 |
| 5. | Neighbors 2: Sorority Rising | $9,100,000 | $38,336,580 |
| 6. | The Jungle Book | $6,967,000 | $338,478,809 |
| 7. | The Nice Guys | $6,370,000 | $21,733,672 |
| 8. | Money Monster | $4,250,000 | $33,902,226 |
| 9. | Love & Friendship | $2,496,000 | $3,489,548 |
| 10. | Zootopia | $831,000 | $335,874,645 |
(vía BoxOfficeMojo)
